COVID-19 Sequencing Project

Upon the emergence of the first COVID-19 case in Jordan back in March 2020, Biolab's research department headed by Dr. Issa Abu-Dayyeh and our molecular diagnostics team immediately launched a unique and nationally unprecedented project that aimed to sequence SARS-CoV2 viruses from Jordan in collaboration with the prestigious Andersen Laboratory from the SCRIPPS Institute, USA.

The project falls within the realm of genetic epidemiology. The main goal is to molecularly characterize the viruses that we have in Jordan, and monitor for the changes that occur to their RNA sequences over time.

This ongoing project has several uses/applications including:

  1. Understanding the possible geographical route(s) the virus took to arrive from Wuhan, China to the Kingdom.
  2. Categorizing the clades found in Jordan and assessing their prevalence in comparison to other countries around the world.
  3. Unraveling nucleic and amino acid mutations in the various genes of Jordanian COVID-19 viruses.
  4. Identifying  special molecular signatures for the Jordanian viruses and utilizing them to monitor COVID-19 spread to and from the country in the past, present, and future.
  5. Spotting any Jordan-specific mutations, and evaluating their potential role in affecting viral  infectivity or disease severity.
  6. Screening for any potential vaccine escape mutants, and evaluating the potential efficacy of upcoming vaccines in controlling viral spread in the country.

To date, our research team has published hundreds of viral sequences on the Global Initiative on Sharing All Influenza Data (GISAID). Those sequences are made freely available to all scientists across the world to benefit from and build on.

For any enquiries regarding the published sequences or their use in your research projects, please contact our project lead Dr. Issa Abu-Dayyeh at i.abudayyeh@biolab.jo

To view our published sequences and the Middle East Phylodynamics map, please check the map below:


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